Aortic stenosis and malformations of the gastrointestinal tract

Aortic stenosis and malformations of the gastrointestinal tractA new study confirmed an increase in the frequency of aortic stenosis in patients with arteriovenous malformations of the gastrointestinal tract. "The combination of arterio-venous malformations (AVM) of the gastrointestinal tract and aortic stenosis was named Heyde syndrome" Refine Dr. Pelin Batur and his colleagues (Cleveland Clinic Foundation, Ohio) in the August issue of Archives of Internal Medicine. "However, remained doubtful, whether there is this syndrome in the daily practice of a physician". The researchers analyzed the medical history of all patients from the database, Cleveland Clinic, whose AVM were diagnosed in the period from 1999 to 2000, when FGDS or mesenteric angioplasty. Mapped the prevalence of aortic and mitral stenosis in 73 patients with AVM, who underwent Echocardiography. Mitral stenosis was selected for comparison, "because he Tadeu same frequency is reason for holding Echocardiography". For comparison with the General population was estimated prevalence of aortic and mitral stenosis in all patients who from 1999 to 2000 was performed Echocardiography. It turned out that aortic stenosis was found in 31.7% of patients with AVM - much more often than in the General population (14.0%; p<0.001). The prevalence of mitral stenosis were, respectively, 1.6% versus 6.0%. Compared with the General population, in patients with AVM was 2.6 times higher risk of clinically significant aortic stenosis and in 4.1 the risk of severe aortic stenosis. "Clinicians should be aware of this syndrome, because it can significantly affect the tactics of management of patients with gastrointestinal bleeding and/or aortic stenosis", conclude the researchers. (Arch Intern Med 2003;163:1821-4).

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