Scientists have grown inside the mouse a tiny human kidney

Scientists have grown inside the mouse a tiny human kidneyScientists have grown inside the mouse a tiny human kidney Using the technique, which could mean the end organ transplantation, scientists have grown miniature human kidney inside the mouse. Kidney, though tiny, works, and from this it follows that patients suffering from dysfunction of this organ, will ever be able to grow your own replacement. In an article published yesterday in Nature Medicine, a team of scientists from Israel reported, as were grown organs from embryonic, stem cells, i.e. cells "parent", who have yet to become specialized, distributed than they are in adulthood will become adult tissue or organs of the body. These cells are taken from embryos, human, and swine, and transplanted to mice, where they grew into a perfect human kidney and pigs, only the size of a mouse, according to today's Daily Telegraph article, the translation of which is published "Miniature human kidney and pig functioned, producing urine. In addition, the blood inside the kidneys were delivered "master" blood vessels, not the donor, significantly reduced the risk of rejection," says the representative of the Israeli scientists working in the research Institute named Weizmann in Rehovot (Rehovot). Scientists, heads of which Professor Yair Reisner, found that the risk of rejection most small when transplanted cells taken from a human embryo age from seven to eight weeks, and pork - at four weeks the embryo. If the cells to be transplanted before the buds grow defective and include muscle, bone, and cartilage cells. At a later age too great a risk of rejection. To see how to adjust to the new kidney is the human immune system, researchers have raised the body of a mouse, completely devoid of the immune system and introduced her human lymphocytes (white blood cells). It was found that if the stem cells from the kidney to transplant in time, the lymphocytes do not attack the new kidney is neither human, nor pork. The study is currently in preclinical stage, and if all goes well, in a few years the system will be tested on humans. Only in Britain more than five thousand people waiting for a kidney transplant. This crisis has led scientists to investigate whether patients to grow implants kidneys from stem cells. They also consider the possibility of kidney transplantation from genetically modified pigs. "Any kind of scientific progress, which will help to cope with a chronic shortage of organs for the benefit of patients. If it is a method of using stem cells, is excellent, although, of course, still only the initial stage of work", - said the representative of the British national research Foundation kidney. Due to ethical issues arising from the use of stem cells in the embryo, it is possible that stem cells pigs would be preferable for doctors and patients. There is hope that stem cells porcine embryo is unlikely to trigger a strong reaction of rejection observed in the transplantation of organs from animals entirely. The kidneys filter toxins contained in the blood and excrete them in the urine. Every day this organ filters about 200 liters of blood, that is 7-8 times runs through the entire volume in the body. Reasons for failure in kidney include, among others, diabetes, high blood pressure, drug abuse, cancer and kidney stones. Source:

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